Event Series:
Young Adults
Jan 20 @ 8:00 pm - 9:00 pm
Young Adults Monthly Meeting
8:00 pm ET | 7:00 pm CT | 6:00 pm MT | 5:00 pm PT
Our guest this month is Mark Tarnopolsky, MD PhD, professor of pediatrics and medicine and director of the Neuromuscular and Neurometabolic Clinic at McMaster University Medical Center in Hamilton, Ontario, Canada. Dr. Tarnopolsky is also CEO and CSO of Exerkine Corporation. He sees a large number of FSHD patients in his clinic and has observed that exercise provides significant benefits to them. He’ll present on this topic and answer your questions.
Research in Dr. Tarnopolsky’s lab investigates the role of exercise and antioxidants as potential therapeutic interventions for FSHD. He explains, “FSHD is a genetic disorder that results from the toxic over-expression of the DUX4 gene, leading to skeletal muscle atrophy and weakness. The final common pathways of cellular dysfunction in this disorder are similar to other muscle diseases (i.e., myotonic MD, mitochondrial disease and sporadic inclusion body myopathy) and human aging associated muscle weakness (sarcopenia) and include; muscle stem cell dysfunction, mitochondrial dysfunction, oxidative stress and a reduction in muscle protein synthesis. We and others have shown the long-term clinical benefit from exercise in DM1, aging and mitochondrial disease and will present encouraging data on the long-term benefit of exercise in FSHD. Furthermore, appropriately targeted multi-ingredient dietary approaches represent a form of “nutra-pharmaceutical” therapy and we have shown significant benefits in aging, obesity and mitochondrial disease. I will discuss the clinical support for optimal dietary nutrient intake and the potential for a multi-ingredient nutrapharmaceutical to target the primary and secondary cellular consequences of FSHD that can be an immediately applied therapy and an adjunct to any future genetic or small molecule approaches.”
FSHD Young Adults is a social and support group focused on encouraging and empowering young adults impacted by FSHD. We created this space specifically for younger FSHDers to connect, collaborate, and provide networking opportunities. Whether you’re just graduating, starting a new position, or already on a career track, the FSHD Young Professionals group will help you develop a valuable network of friends facing similar challenges.
Our group is hosted and facilitated by volunteers who are excited to connect with you. We meet once a month via Zoom. Mark your calendar for the third Monday at 8pm ET/5pm PT. Once you join the group, no need to register again; you will be sent regular reminders and the Zoom link.
You can also join the conversation on Discord.
To contact us directly, please email: youngprofessionals@fshdsociety.org.
